Varaico: Literature-Extracted Genetic Variants

TCF7

210 papers

RefSeq Summary

This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and...

Pfam Domains

CTNNB1_bindingaa 10–212UCSCN-terminal CTNNB1 binding

HMG_boxaa 269–337UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

transcription factor 7

HGNC Alias Symbol

TCF-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003202.5

p.L332P

c.995T>C

Surrounding Variants

2 papers

NM_003202.5

p.W336C

c.1008G>C

2 papers

NM_003202.5

p.W336C

c.1008G>T

1 paper

NM_003202.5

p.S337fs

c.1009_1010fs

1 paper

NM_003202.5

p.N341K

c.1023C>A

1 paper

NM_003202.5

p.A316T

c.946G>A

1 paper

NM_003202.5

p.R312R

c.934C>A

1 paper

NM_003202.5

p.R305R

c.915C>G

1 paper

NM_003202.5

p.E282K

c.844G>A

1 paper

NM_003202.5

p.A275A

c.825C>T

2 papers

NM_003202.5

p.L273L

c.819C>T

1 paper

NM_003202.5

p.E261K

c.781G>A

1 paper

NM_003202.5

p.S258F

c.773C>T