Varaico: Literature-Extracted Genetic Variants

TCF7L1

120 papers

RefSeq Summary

This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway a...

Pfam Domains

CTNNB1_bindingaa 25–250UCSCN-terminal CTNNB1 binding

HMG_boxaa 346–414UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

transcription factor 7 like 1

HGNC Previous Name

transcription factor 7-like 1 (T-cell specific, HMG-box)

Papers

RefSeq ID

Protein change

DNA change

1–12 of 118 variants

6 papers

NM_031283.3

p.G8del1

c.22_23delGGC

4 papers

NM_031283.3

p.Q3delFs

c.8delA

4 papers

NM_031283.3

p.S22_G24del3

c.64_71del9

3 papers

NM_031283.3

p.Q433*

c.1297C>T

3 papers

NM_031283.3

p.G533R

c.1597G>A

3 papers

NM_031283.3

p.G533R

c.1597G>C

2 papers

NM_031283.3

p.G12D

c.35G>A

2 papers

NM_031283.3

p.R92P

c.275G>C

2 papers

NM_031283.3

p.D216Y

c.646G>T

2 papers

NM_031283.3

p.L236P

c.707T>C

2 papers

NM_031283.3

p.P253S

c.757C>T

2 papers

NM_031283.3

p.R268W

c.802C>T