Varaico: Literature-Extracted Genetic Variants

TCF7L1

120 papers

RefSeq Summary

This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway a...

Pfam Domains

CTNNB1_bindingaa 25–250UCSCN-terminal CTNNB1 binding

HMG_boxaa 346–414UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

transcription factor 7 like 1

HGNC Previous Name

transcription factor 7-like 1 (T-cell specific, HMG-box)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_031283.3

p.K97R

c.290A>G

Surrounding Variants

1 paper

NM_031283.3

p.R99Q

c.296G>A

1 paper

NM_031283.3

p.D93Y

c.277G>T

2 papers

NM_031283.3

p.R92P

c.275G>C

1 paper

NM_031283.3

p.F102_A103insFs

c.306_307insAG

1 paper

NM_031283.3

p.V91I

c.271G>A

1 paper

NM_031283.3

p.E104K

c.310G>A

1 paper

NM_031283.3

p.R86T

c.257G>C

1 paper

NM_031283.3

p.E83_A84Splc

c.249+1G>A

1 paper

NM_031283.3

p.E83K

c.247G>A

1 paper

NM_031283.3

p.E64V

c.191A>T

1 paper

NM_031283.3

p.E64Q

c.190G>C

1 paper

NM_031283.3

p.A58T

c.172G>A