Varaico: Literature-Extracted Genetic Variants

TCF7L1

120 papers

RefSeq Summary

This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway a...

Pfam Domains

CTNNB1_bindingaa 25–250UCSCN-terminal CTNNB1 binding

HMG_boxaa 346–414UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

transcription factor 7 like 1

HGNC Previous Name

transcription factor 7-like 1 (T-cell specific, HMG-box)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_031283.3

p.R268W

c.802C>T

Surrounding Variants

1 paper

NM_031283.3

p.Y260insFs

c.778_779insA

1 paper

NM_031283.3

p.N277_A278del1

c.831_833delCGC

1 paper

NM_031283.3

p.N277K

c.831C>A

1 paper

NM_031283.3

p.N277K

c.831C>G

1 paper

NM_031283.3

p.P253P

c.759A>C

2 papers

NM_031283.3

p.P253S

c.757C>T

1 paper

NM_031283.3

p.V252I

c.754G>A

1 paper

NM_031283.3

p.L248H

c.743T>A

1 paper

NM_031283.3

p.H246P

c.737A>C

1 paper

NM_031283.3

p.H246insFs

c.736dupC

1 paper

NM_031283.3

p.S237F

c.710C>T

2 papers

NM_031283.3

p.L236P

c.707T>C