Varaico: Literature-Extracted Genetic Variants

TCF7L1

120 papers

RefSeq Summary

This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway a...

Pfam Domains

CTNNB1_bindingaa 25–250UCSCN-terminal CTNNB1 binding

HMG_boxaa 346–414UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

transcription factor 7 like 1

HGNC Previous Name

transcription factor 7-like 1 (T-cell specific, HMG-box)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_031283.3

p.A366V

c.1097C>T

Surrounding Variants

1 paper

NM_031283.3

p.M357I

c.1071G>A

1 paper

NM_031283.3

p.M357I

c.1071G>C

1 paper

NM_031283.3

p.M357I

c.1071G>T

1 paper

NM_031283.3

p.Q378E

c.1132C>G

1 paper

NM_031283.3

p.V336M

c.1006G>A

1 paper

NM_031283.3

p.T335Fs

c.1003delinsGAFs

1 paper

NM_031283.3

p.N386K

c.1158C>A

1 paper

NM_031283.3

p.N386K

c.1158C>G

1 paper

NM_031283.3

p.L387P

c.1160T>C

1 paper

NM_031283.3

p.Y396H

c.1186T>C

2 papers

NM_031283.3

p.R400Q

c.1199G>A

1 paper

NM_031283.3

p.P411L

c.1232C>T