Varaico: Literature-Extracted Genetic Variants

TCF7L1

120 papers

RefSeq Summary

This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway a...

Pfam Domains

CTNNB1_bindingaa 25–250UCSCN-terminal CTNNB1 binding

HMG_boxaa 346–414UCSCHMG (high mobility group) box

Gene Aliases

HGNC Name

transcription factor 7 like 1

HGNC Previous Name

transcription factor 7-like 1 (T-cell specific, HMG-box)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_031283.3

p.P563P

c.1689C>T

Surrounding Variants

2 papers

NM_031283.3

p.A564T

c.1690G>A

1 paper

NM_031283.3

p.P559T

c.1675C>A

1 paper

NM_031283.3

p.Q570H

c.1710G>C

1 paper

NM_031283.3

p.Q570H

c.1710G>T

2 papers

NM_031283.3

p.P573L

c.1718C>T

2 papers

NM_031283.3

p.T553I

c.1658C>T

1 paper

NM_031283.3

p.G549W

c.1645G>T

3 papers

NM_031283.3

p.G533R

c.1597G>A

3 papers

NM_031283.3

p.G533R

c.1597G>C

2 papers

NM_031283.3

p.A520G

c.1559C>G

1 paper

NM_031283.3

p.S519C

c.1556C>G

2 papers

NM_031283.3

p.A516S

c.1546G>T