Varaico: Literature-Extracted Genetic Variants

Gene:TDO2
Variant:p.N10H

TDO2

72 papers

RefSeq Summary

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein ...

Pfam Domains

Trp_dioxygenaseaa 26–372UCSCTryptophan 2,3-dioxygenase

Gene Aliases

HGNC Name

tryptophan 2,3-dioxygenase

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005651.4
p.N10H
c.28A>C
Surrounding Variants
1 paper
NM_005651.4
p.N10D
c.28A>G
1 paper
NM_005651.4
p.G8G
c.24A>G
1 paper
NM_005651.4
p.G8G
c.24A>T
1 paper
NM_005651.4
p.F11F
c.33T>C
1 paper
NM_005651.4
p.G12*
c.34G>T
1 paper
NM_005651.4
p.G3G
c.9G>A
1 paper
NM_005651.4
p.M1K
c.2T>A
1 paper
NM_005651.4
p.M1T
c.2T>C
1 paper
NM_005651.4
p.K17R
c.50A>G
1 paper
NM_005651.4
p.V20I
c.58G>A
1 paper
NM_005651.4
p.V20E
c.59T>A
1 paper
NM_005651.4
p.V20G
c.59T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."