Varaico: Literature-Extracted Genetic Variants

Gene:TDO2
Variant:p.S151A

TDO2

72 papers

RefSeq Summary

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein ...

Pfam Domains

Trp_dioxygenaseaa 26–372UCSCTryptophan 2,3-dioxygenase

Gene Aliases

HGNC Name

tryptophan 2,3-dioxygenase

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005651.4
p.S151A
c.451T>G
Surrounding Variants
1 paper
NM_005651.4
p.S151T
c.451T>A
2 papers
NM_005651.4
p.K164insFs
c.491dupA
1 paper
NM_005651.4
p.I165fs
c.493_494fs
1 paper
NM_005651.4
p.T136A
c.406A>G
1 paper
NM_005651.4
p.V126G
c.377T>G
1 paper
NM_005651.4
p.R117*
c.349C>T
1 paper
NM_005651.4
p.L109L
c.327T>A
4 papers
NM_005651.4
p.M108I
c.324G>A
3 papers
NM_005651.4
p.M108I
c.324G>C
4 papers
NM_005651.4
p.M108I
c.324G>T
1 paper
NM_005651.4
p.N107fs
c.319_320fs
1 paper
NM_005651.4
p.F222C
c.665T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."