Varaico: Literature-Extracted Genetic Variants

Gene:TDO2
Variant:p.G341V

TDO2

72 papers

RefSeq Summary

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein ...

Pfam Domains

Trp_dioxygenaseaa 26–372UCSCTryptophan 2,3-dioxygenase

Gene Aliases

HGNC Name

tryptophan 2,3-dioxygenase

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005651.4
p.G341V
c.1022G>T
Surrounding Variants
1 paper
NM_005651.4
p.G341D
c.1022G>A
1 paper
NM_005651.4
p.G343D
c.1028G>A
1 paper
NM_005651.4
p.R334G
c.1000A>G
1 paper
NM_005651.4
p.R325T
c.974G>C
2 papers
NM_005651.4
p.Y359*
c.1077C>A
2 papers
NM_005651.4
p.Y359*
c.1077C>G
1 paper
NM_005651.4
p.I373T
c.1118T>C
1 paper
NM_005651.4
p.K380N
c.1140G>C
1 paper
NM_005651.4
p.K380N
c.1140G>T
1 paper
NM_005651.4
p.S398A
c.1192T>G
1 paper
NM_005651.4
p.R299W
c.895A>T
3 papers
NM_005651.4
p.F268Y
c.803T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."