Varaico: Literature-Extracted Genetic Variants

Gene:TDP2
Variant:p.G217fs

TDP2

75 papers

RefSeq Summary

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associat...

Pfam Domains

UBA_4aa 28–67UCSCUBA-like domain
Exo_endo_phosaa 117–351UCSCEndonuclease/Exonuclease/phosphatase family

Gene Aliases

HGNC Name

tyrosyl-DNA phosphodiesterase 2

HGNC Previous Symbol

TTRAP

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_016614.3
p.G217fs
c.649_650fs
Surrounding Variants
3 papers
NM_016614.3
p.G217delFs
c.650delC
1 paper
NM_016614.3
p.H212_V213Splc
c.637-1G>T
1 paper
NM_016614.3
p.T230fs
c.688_689fs
1 paper
NM_016614.3
p.R237*
c.709C>T
2 papers
NM_016614.3
p.M238fs
c.712_713fs
2 papers
NM_016614.3
p.M238_N239delFs
c.714_717del4
1 paper
NM_016614.3
p.M243fs
c.727_728fs
1 paper
NM_016614.3
p.M243delFs
c.728delA
2 papers
NM_016614.3
p.Q249E
c.745C>G
1 paper
NM_016614.3
p.D262N
c.784G>A
3 papers
NM_016614.3
p.D262A
c.785A>C
1 paper
NM_016614.3
p.R268Q
c.803G>A
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