Varaico: Literature-Extracted Genetic Variants

Gene:TDP2
Variant:p.S60A

TDP2

75 papers

RefSeq Summary

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associat...

Pfam Domains

UBA_4aa 28–67UCSCUBA-like domain
Exo_endo_phosaa 117–351UCSCEndonuclease/Exonuclease/phosphatase family

Gene Aliases

HGNC Name

tyrosyl-DNA phosphodiesterase 2

HGNC Previous Symbol

TTRAP

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_016614.3
p.S60A
c.178T>G
Surrounding Variants
2 papers
NM_016614.3
p.N59D
c.175A>G
1 paper
NM_016614.3
p.E53Q
c.157G>C
1 paper
NM_016614.3
p.D51N
c.151G>A
1 paper
NM_016614.3
p.D39N
c.115G>A
1 paper
NM_016614.3
p.A36P
c.106G>C
1 paper
NM_016614.3
p.F32L
c.96T>G
1 paper
NM_016614.3
p.F32L
c.96T>A
1 paper
NM_016614.3
p.F32L
c.94T>C
1 paper
NM_016614.3
p.V30M
c.88G>A
1 paper
NM_016614.3
p.R26P
c.77G>C
1 paper
NM_016614.3
p.R25R
c.75G>C
1 paper
NM_016614.3
p.K24R
c.71A>G
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