Varaico: Literature-Extracted Genetic Variants

TEC

165 papers

RefSeq Summary

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signal...

Pfam Domains

PHaa 5–111UCSCPH domain

BTKaa 119–148UCSCBTK motif

SH3_1aa 185–231UCSCSH3 domain

SH2aa 247–330UCSCSH2 domain

PK_Tyr_Ser-Thraa 370–619UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

tec protein tyrosine kinase

HGNC Alias Symbol

PSCTK4

Papers

RefSeq ID

Protein change

DNA change

1–12 of 126 variants

3 papers

NM_003215.3

p.V234I

c.700G>A

2 papers

NM_003215.3

p.F92L

c.274T>C

2 papers

NM_003215.3

p.F92L

c.276T>G

2 papers

NM_003215.3

p.F92L

c.276T>A

2 papers

NM_003215.3

p.W363_S368del0

c.1089_1103del15

2 papers

NM_003215.3

p.A396T

c.1186G>A

2 papers

NM_003215.3

p.P423P

c.1269G>A

1 paper

NM_003215.3

p.N4K

c.12C>A

1 paper

NM_003215.3

p.I10insFs

c.29_30insC

1 paper

NM_003215.3

p.K13R

c.38A>G

1 paper

NM_003215.3

p.S15*

c.44C>A

1 paper

NM_003215.3

p.T21A

c.61A>G