Varaico: Literature-Extracted Genetic Variants

TEC

165 papers

RefSeq Summary

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signal...

Pfam Domains

PHaa 5–111UCSCPH domain

BTKaa 119–148UCSCBTK motif

SH3_1aa 185–231UCSCSH3 domain

SH2aa 247–330UCSCSH2 domain

PK_Tyr_Ser-Thraa 370–619UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

tec protein tyrosine kinase

HGNC Alias Symbol

PSCTK4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003215.3

p.D472V

c.1415A>T

Surrounding Variants

1 paper

NM_003215.3

p.V473M

c.1417G>A

1 paper

NM_003215.3

p.E475*

c.1423G>T

1 paper

NM_003215.3

p.E475G

c.1424A>G

1 paper

NM_003215.3

p.D464_L467delFs

c.1392_1401del10

1 paper

NM_003215.3

p.E478_Y479insT

c.1432_1436ins3

1 paper

NM_003215.3

p.V465I

c.1393G>A

1 paper

NM_003215.3

p.S484C

c.1450A>T

1 paper

NM_003215.3

p.S484G

c.1450A>G

1 paper

NM_003215.3

p.Q458H

c.1374A>T

1 paper

NM_003215.3

p.F453insFs

c.1357_1358insG

1 paper

NM_003215.3

p.K436insFs

c.1307_1308insA

1 paper

NM_003215.3

p.T433S

c.1297A>T