Varaico: Literature-Extracted Genetic Variants

TEC

165 papers

RefSeq Summary

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signal...

Pfam Domains

PHaa 5–111UCSCPH domain

BTKaa 119–148UCSCBTK motif

SH3_1aa 185–231UCSCSH3 domain

SH2aa 247–330UCSCSH2 domain

PK_Tyr_Ser-Thraa 370–619UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

tec protein tyrosine kinase

HGNC Alias Symbol

PSCTK4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003215.3

p.M418L

c.1252A>C

Surrounding Variants

1 paper

NM_003215.3

p.R401_C406delFs

c.1201_1216del16

1 paper

NM_003215.3

p.A404delFs

c.1212delT

1 paper

NM_003215.3

p.I397M

c.1191C>G

2 papers

NM_003215.3

p.A396T

c.1186G>A

1 paper

NM_003215.3

p.R385K

c.1154G>A

1 paper

NM_003215.3

p.L420M

c.1258C>A

2 papers

NM_003215.3

p.P423P

c.1269G>A

1 paper

NM_003215.3

p.R374R

c.1122G>A

1 paper

NM_003215.3

p.M373L

c.1117A>T

1 paper

NM_003215.3

p.M373L

c.1117A>C

2 papers

NM_003215.3

p.W363_S368del0

c.1089_1103del15

1 paper

NM_003215.3

p.T433S

c.1297A>T