Varaico: Literature-Extracted Genetic Variants

TEC

165 papers

RefSeq Summary

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signal...

Pfam Domains

PHaa 5–111UCSCPH domain

BTKaa 119–148UCSCBTK motif

SH3_1aa 185–231UCSCSH3 domain

SH2aa 247–330UCSCSH2 domain

PK_Tyr_Ser-Thraa 370–619UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

tec protein tyrosine kinase

HGNC Alias Symbol

PSCTK4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003215.3

p.G224R

c.670G>A

Surrounding Variants

1 paper

NM_003215.3

p.D213Y

c.637G>T

1 paper

NM_003215.3

p.E210K

c.628G>A

1 paper

NM_003215.3

p.E194A

c.581A>C

1 paper

NM_003215.3

p.E194K

c.580G>A

1 paper

NM_003215.3

p.I183M

c.549C>G

1 paper

NM_003215.3

p.E182A

c.545A>C

1 paper

NM_003215.3

p.E177_D178del2

c.529_533del6

1 paper

NM_003215.3

p.E177_D178del1

c.531_533delTCT

1 paper

NM_003215.3

p.P173S

c.517C>T

1 paper

NM_003215.3

p.P173T

c.517C>A

1 paper

NM_003215.3

p.P170Q

c.509C>A

1 paper

NM_003215.3

p.P169S

c.505C>T