Varaico: Literature-Extracted Genetic Variants

TEC

165 papers

RefSeq Summary

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signal...

Pfam Domains

PHaa 5–111UCSCPH domain

BTKaa 119–148UCSCBTK motif

SH3_1aa 185–231UCSCSH3 domain

SH2aa 247–330UCSCSH2 domain

PK_Tyr_Ser-Thraa 370–619UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

tec protein tyrosine kinase

HGNC Alias Symbol

PSCTK4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003215.3

p.N147H

c.439A>C

Surrounding Variants

1 paper

NM_003215.3

p.S151S

c.453C>T

1 paper

NM_003215.3

p.G142R

c.424G>C

1 paper

NM_003215.3

p.G142R

c.424G>A

1 paper

NM_003215.3

p.P141S

c.421C>T

1 paper

NM_003215.3

p.E109K

c.325G>A

1 paper

NM_003215.3

p.K107R

c.320A>G

2 papers

NM_003215.3

p.F92L

c.276T>G

2 papers

NM_003215.3

p.F92L

c.276T>A

2 papers

NM_003215.3

p.F92L

c.274T>C

1 paper

NM_003215.3

p.D85Y

c.253G>T

1 paper

NM_003215.3

p.V82A

c.245T>C

1 paper

NM_003215.3

p.A156T

c.466G>A