Varaico: Literature-Extracted Genetic Variants

TEC

165 papers

RefSeq Summary

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signal...

Pfam Domains

PHaa 5–111UCSCPH domain

BTKaa 119–148UCSCBTK motif

SH3_1aa 185–231UCSCSH3 domain

SH2aa 247–330UCSCSH2 domain

PK_Tyr_Ser-Thraa 370–619UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

tec protein tyrosine kinase

HGNC Alias Symbol

PSCTK4

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003215.3

p.K13R

c.38A>G

Surrounding Variants

1 paper

NM_003215.3

p.S15*

c.44C>A

1 paper

NM_003215.3

p.I10insFs

c.29_30insC

1 paper

NM_003215.3

p.T21A

c.61A>G

1 paper

NM_003215.3

p.T21I

c.62C>T

1 paper

NM_003215.3

p.N4K

c.12C>A

1 paper

NM_003215.3

p.Y26F

c.77A>T

1 paper

NM_003215.3

p.K27Q

c.79A>C

1 paper

NM_003215.3

p.K35R

c.104A>G

1 paper

NM_003215.3

p.S36P

c.106T>C

1 paper

NM_003215.3

p.Y41C

c.122A>G

1 paper

NM_003215.3

p.G43D

c.128G>A

1 paper

NM_003215.3

p.R44Q

c.131G>A