Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.Y61S

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001127208.3
p.Y61S
c.182A>C
Surrounding Variants
1 paper
NM_001127208.3
p.Y61insFs
c.183dupT
1 paper
NM_001127208.3
p.Y61F
c.182A>T
1 paper
NM_001127208.3
p.Y61*
c.183T>A
1 paper
NM_001127208.3
p.Y61*
c.183T>G
1 paper
NM_001127208.3
p.Y61fs
c.181_182fs
1 paper
NM_001127208.3
p.G62fs
c.184_185fs
1 paper
NM_001127208.3
p.Y60*
c.180T>A
1 paper
NM_001127208.3
p.Y60*
c.180T>G
1 paper
NM_001127208.3
p.Y60_Y61insFs
c.180_181ins5
1 paper
NM_001127208.3
p.Y60S
c.179A>C
1 paper
NM_001127208.3
p.Y60C
c.179A>G
1 paper
NM_001127208.3
p.G62_I63insFs
c.186_187insCA
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."