Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.Y437fs

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001127208.3
p.Y437fs
c.1309_1310fs
Surrounding Variants
1 paper
NM_001127208.3
p.Y437H
c.1309T>C
1 paper
NM_001127208.3
p.P438insFs
c.1314dupC
1 paper
NM_001127208.3
p.P438delFs
c.1314delC
1 paper
NM_001127208.3
p.H436Q
c.1308C>G
1 paper
NM_001127208.3
p.H436_Y437delFs
c.1308_1311del4
5 papers
NM_001127208.3
p.Y437*
c.1311C>A
6 papers
NM_001127208.3
p.Y437*
c.1311C>G
2 papers
NM_001127208.3
p.H436fs
c.1306_1307fs
2 papers
NM_001127208.3
p.P438S
c.1312C>T
1 paper
NM_001127208.3
p.H436delFs
c.1307delA
2 papers
NM_001127208.3
p.H436fs
c.1306_1307fs
1 paper
NM_001127208.3
p.H435insFs
c.1304_1305insT
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