Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.G645insFs

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001127208.3
p.G645insFs
c.1935dupT
Surrounding Variants
1 paper
NM_001127208.3
p.G645C
c.1933G>T
1 paper
NM_001127208.3
p.G645fs
c.1933_1934fs
2 papers
NM_001127208.3
p.T646insFs
c.1936dupA
1 paper
NM_001127208.3
p.T646del1
c.1936_1937delACA
10 papers
NM_001127208.3
p.G645insFs
c.1934dupG
3 papers
NM_001127208.3
p.T646fs
c.1936_1937fs
1 paper
NM_001127208.3
p.T646delFs
c.1937delC
1 paper
NM_001127208.3
p.T646fs
c.1936_1937fs
1 paper
NM_001127208.3
p.G645delFs
c.1934delG
1 paper
NM_001127208.3
p.T646insFs
c.1937_1938ins5
14 papers
NM_001127208.3
p.Q644*
c.1930C>T
1 paper
NM_001127208.3
p.Q644delFs
c.1932delA
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."