Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.L853fs

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001127208.3
p.L853fs
c.2557_2558fs
Surrounding Variants
1 paper
NM_001127208.3
p.F854insFs
c.2562dupT
3 papers
NM_001127208.3
p.F854delFs
c.2562delT
1 paper
NM_001127208.3
p.E852G
c.2555A>G
1 paper
NM_001127208.3
p.E852K
c.2554G>A
4 papers
NM_001127208.3
p.E852*
c.2554G>T
1 paper
NM_001127208.3
p.E852fs
c.2554_2555fs
2 papers
NM_001127208.3
p.F854fs
c.2560_2561fs
1 paper
NM_001127208.3
p.F854fs
c.2560_2561fs
1 paper
NM_001127208.3
p.P851insFs
c.2553dupT
1 paper
NM_001127208.3
p.P851delFs
c.2553delT
5 papers
NM_001127208.3
p.P851fs
c.2551_2552fs
1 paper
NM_001127208.3
p.P851fs
c.2551_2552fs
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