Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.M865L

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001127208.3
p.M865L
c.2593A>C
Surrounding Variants
2 papers
NM_001127208.3
p.M865fs
c.2593_2594fs
1 paper
NM_001127208.3
p.M865V
c.2593A>G
1 paper
NM_001127208.3
p.M865L
c.2593A>T
1 paper
NM_001127208.3
p.M865fs
c.2593_2594fs
1 paper
NM_001127208.3
p.Q866_V872del7
c.2596_2615del21
1 paper
NM_001127208.3
p.M865delFs
c.2593delA
1 paper
NM_001127208.3
p.M865_Q866delFs
c.2593_2597del5
1 paper
NM_001127208.3
p.M865insFs
c.2594_2595insG
1 paper
NM_001127208.3
p.M865I
c.2595G>A
1 paper
NM_001127208.3
p.M865I
c.2595G>C
1 paper
NM_001127208.3
p.M865I
c.2595G>T
1 paper
NM_001127208.3
p.Q866fs
c.2596_2597fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."