Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.Q866Q

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001127208.3
p.Q866Q
c.2598A>G
Surrounding Variants
59 papers
NM_001127208.3
p.Y867H
c.2599T>C
1 paper
NM_001127208.3
p.Y867S
c.2600A>C
1 paper
NM_001127208.3
p.Y867C
c.2600A>G
1 paper
NM_001127208.3
p.Y867delFs
c.2601delT
1 paper
NM_001127208.3
p.Q866fs
c.2596_2597fs
14 papers
NM_001127208.3
p.Q866*
c.2596C>T
1 paper
NM_001127208.3
p.Q866_V872delFs
c.2597_2616del20
1 paper
NM_001127208.3
p.M865I
c.2595G>A
1 paper
NM_001127208.3
p.M865I
c.2595G>C
1 paper
NM_001127208.3
p.M865I
c.2595G>T
5 papers
NM_001127208.3
p.Y867*
c.2601T>A
5 papers
NM_001127208.3
p.Y867*
c.2601T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."