Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.F868L

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
48 papers
NM_001127208.3
p.F868L
c.2604T>G
Surrounding Variants
45 papers
NM_001127208.3
p.F868L
c.2604T>A
1 paper
NM_001127208.3
p.F868_P869insFs
c.2604_2605insG
1 paper
NM_001127208.3
p.P869fs
c.2605_2606fs
1 paper
NM_001127208.3
p.N870delFs
c.2609delA
45 papers
NM_001127208.3
p.F868L
c.2602T>C
5 papers
NM_001127208.3
p.Y867*
c.2601T>A
5 papers
NM_001127208.3
p.Y867*
c.2601T>G
1 paper
NM_001127208.3
p.N870fs
c.2608_2609fs
1 paper
NM_001127208.3
p.Y867S
c.2600A>C
1 paper
NM_001127208.3
p.Y867C
c.2600A>G
1 paper
NM_001127208.3
p.Y867delFs
c.2601delT
1 paper
NM_001127208.3
p.N870S
c.2609A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."