Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.Q876fs

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001127208.3
p.Q876fs
c.2626_2627fs
Surrounding Variants
12 papers
NM_001127208.3
p.Q876*
c.2626C>T
1 paper
NM_001127208.3
p.Q876P
c.2627A>C
1 paper
NM_001127208.3
p.K875fs
c.2623_2624fs
1 paper
NM_001127208.3
p.D877fs
c.2629_2630fs
1 paper
NM_001127208.3
p.P874_K875ins2
c.2622_2623ins6
1 paper
NM_001127208.3
p.D877insFs
c.2631dupT
1 paper
NM_001127208.3
p.D877G
c.2630A>G
1 paper
NM_001127208.3
p.D877E
c.2631T>A
1 paper
NM_001127208.3
p.D877E
c.2631T>G
1 paper
NM_001127208.3
p.L878delFs
c.2632delC
2 papers
NM_001127208.3
p.L878fs
c.2632_2633fs
1 paper
NM_001127208.3
p.P874A
c.2620C>G
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