Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.L878fs

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001127208.3
p.L878fs
c.2632_2633fs
Surrounding Variants
2 papers
NM_001127208.3
p.L878fs
c.2632_2633fs
1 paper
NM_001127208.3
p.D877E
c.2631T>A
1 paper
NM_001127208.3
p.L878P
c.2633T>C
1 paper
NM_001127208.3
p.D877E
c.2631T>G
1 paper
NM_001127208.3
p.L878delFs
c.2632delC
1 paper
NM_001127208.3
p.D877insFs
c.2631dupT
1 paper
NM_001127208.3
p.D877G
c.2630A>G
1 paper
NM_001127208.3
p.L879fs
c.2635_2636fs
1 paper
NM_001127208.3
p.D877fs
c.2629_2630fs
1 paper
NM_001127208.3
p.Q876P
c.2627A>C
1 paper
NM_001127208.3
p.L879_H880insFs
c.2637_2638insA
1 paper
NM_001127208.3
p.H880delFs
c.2638delC
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."