Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.R881insFs

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001127208.3
p.R881insFs
c.2641_2642ins5
Surrounding Variants
3 papers
NM_001127208.3
p.H880R
c.2639A>G
1 paper
NM_001127208.3
p.H880Q
c.2640C>A
1 paper
NM_001127208.3
p.H880Q
c.2640C>G
2 papers
NM_001127208.3
p.R881fs
c.2641_2642fs
1 paper
NM_001127208.3
p.R881W
c.2641A>T
1 paper
NM_001127208.3
p.R881delFs
c.2643delG
1 paper
NM_001127208.3
p.R881fs
c.2641_2642fs
1 paper
NM_001127208.3
p.L879_H880insFs
c.2637_2638insA
1 paper
NM_001127208.3
p.H880delFs
c.2638delC
1 paper
NM_001127208.3
p.R881K
c.2642G>A
1 paper
NM_001127208.3
p.L879fs
c.2635_2636fs
1 paper
NM_001127208.3
p.R881R
c.2643G>A
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