Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.G1361S

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
6 papers
NM_001127208.3
p.G1361S
c.4081G>A
Surrounding Variants
5 papers
NM_001127208.3
p.G1361R
c.4081G>C
5 papers
NM_001127208.3
p.G1361C
c.4081G>T
1 paper
NM_001127208.3
p.G1361fs
c.4081_4082fs
12 papers
NM_001127208.3
p.G1361D
c.4082G>A
3 papers
NM_001127208.3
p.G1361V
c.4082G>T
8 papers
NM_001127208.3
p.L1360Q
c.4079T>A
3 papers
NM_001127208.3
p.L1360P
c.4079T>C
3 papers
NM_001127208.3
p.L1360R
c.4079T>G
1 paper
NM_001127208.3
p.G1361G
c.4083T>G
1 paper
NM_001127208.3
p.L1360delFs
c.4080delG
1 paper
NM_001127208.3
p.L1360M
c.4078C>A
1 paper
NM_001127208.3
p.L1360fs
c.4078_4079fs
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."