Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.M1456delFs

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001127208.3
p.M1456delFs
c.4367_4368delTG
Surrounding Variants
1 paper
NM_001127208.3
p.M1456del1
c.4366_4367delATG
1 paper
NM_001127208.3
p.R1455fs
c.4363_4364fs
2 papers
NM_001127208.3
p.R1455G
c.4363A>G
1 paper
NM_001127208.3
p.R1455fs
c.4363_4364fs
1 paper
NM_001127208.3
p.V1454insFs
c.4361_4362insG
1 paper
NM_001127208.3
p.V1454I
c.4360G>A
1 paper
NM_001127208.3
p.E1459_T1463delFs
c.4375_4387del13
1 paper
NM_001127208.3
p.K1453*
c.4357A>T
5 papers
NM_001127208.3
p.R1452Q
c.4355G>A
1 paper
NM_001127208.3
p.R1452P
c.4355G>C
1 paper
NM_001127208.3
p.R1452delFs
c.4356delA
1 paper
NM_001127208.3
p.P1460insFs
c.4378_4379insG
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."