Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.V1461F

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001127208.3
p.V1461F
c.4381G>T
Surrounding Variants
1 paper
NM_001127208.3
p.V1461insFs
c.4383dupC
2 papers
NM_001127208.3
p.P1460insFs
c.4380dupA
1 paper
NM_001127208.3
p.P1460delFs
c.4380delA
1 paper
NM_001127208.3
p.K1462delFs
c.4385delA
2 papers
NM_001127208.3
p.K1462fs
c.4384_4385fs
1 paper
NM_001127208.3
p.P1460insFs
c.4378_4379insG
1 paper
NM_001127208.3
p.P1460fs
c.4378_4379fs
1 paper
NM_001127208.3
p.K1462R
c.4385A>G
1 paper
NM_001127208.3
p.T1463S
c.4387A>T
1 paper
NM_001127208.3
p.T1463S
c.4388C>G
1 paper
NM_001127208.3
p.E1459_T1463delFs
c.4375_4387del13
1 paper
NM_001127208.3
p.C1464G
c.4390T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."