Varaico: Literature-Extracted Genetic Variants

Gene:TET2
Variant:p.I1873fs

TET2

2,192 papers

RefSeq Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defect...

Pfam Domains

Tet_JBPaa 1290–1905UCSCOxygenase domain of the 2OGFeDO superfamily

Gene Aliases

HGNC Name

tet methylcytosine dioxygenase 2

HGNC Previous Symbol

KIAA1546

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001127208.3
p.I1873fs
c.5617_5618fs
Surrounding Variants
2 papers
NM_001127208.3
p.I1873L
c.5617A>C
1 paper
NM_001127208.3
p.I1873V
c.5617A>G
1 paper
NM_001127208.3
p.I1873insFs
c.5617dupA
8 papers
NM_001127208.3
p.I1873N
c.5618T>A
114 papers
NM_001127208.3
p.I1873T
c.5618T>C
2 papers
NM_001127208.3
p.I1873S
c.5618T>G
1 paper
NM_001127208.3
p.E1874_C1875del2
c.5620_5624del6
1 paper
NM_001127208.3
p.L1872H
c.5615T>A
9 papers
NM_001127208.3
p.L1872P
c.5615T>C
5 papers
NM_001127208.3
p.L1872R
c.5615T>G
1 paper
NM_001127208.3
p.I1873M
c.5619T>G
1 paper
NM_001127208.3
p.L1872fs
c.5614_5615fs
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."