Varaico: Literature-Extracted Genetic Variants

TFPI2

295 papers

RefSeq Summary

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin...

Pfam Domains

Kunitz_BPTIaa 35–87UCSCKunitz/Bovine pancreatic trypsin inhibitor domain

Kunitz_BPTIaa 95–150UCSCKunitz/Bovine pancreatic trypsin inhibitor domain

Kunitz_BPTIaa 157–209UCSCKunitz/Bovine pancreatic trypsin inhibitor domain

Gene Aliases

HGNC Name

tissue factor pathway inhibitor 2

HGNC Alias Symbols

PP5; TFPI-2; REF1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006528.4

p.R222C

c.664C>T

Surrounding Variants

1 paper

NM_006528.4

p.L221delFs

c.663delA

1 paper

NM_006528.4

p.F223S

c.668T>C

1 paper

NM_006528.4

p.P219L

c.656C>T

1 paper

NM_006528.4

p.S225N

c.674G>A

1 paper

NM_006528.4

p.K232*

c.694A>T

1 paper

NM_006528.4

p.A211Splc

c.631+113C>T

1 paper

NM_006528.4

p.C208Y

c.623G>A

1 paper

NM_006528.4

p.R206L

c.617G>T

1 paper

NM_006528.4

p.G193E

c.578G>A

1 paper

NM_006528.4

p.G190fs

c.568_569fs

2 papers

NM_006528.4

p.T189T

c.567T>C

1 paper

NM_006528.4

p.Y188C

c.563A>G