Varaico: Literature-Extracted Genetic Variants

TFPI2

295 papers

RefSeq Summary

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin...

Pfam Domains

Kunitz_BPTIaa 35–87UCSCKunitz/Bovine pancreatic trypsin inhibitor domain

Kunitz_BPTIaa 95–150UCSCKunitz/Bovine pancreatic trypsin inhibitor domain

Kunitz_BPTIaa 157–209UCSCKunitz/Bovine pancreatic trypsin inhibitor domain

Gene Aliases

HGNC Name

tissue factor pathway inhibitor 2

HGNC Alias Symbols

PP5; TFPI-2; REF1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006528.4

p.A169V

c.506C>T

Surrounding Variants

1 paper

NM_006528.4

p.A169insFs

c.506dupC

1 paper

NM_006528.4

p.R173C

c.517C>T

1 paper

NM_006528.4

p.K162_G165del0

c.485_493del9

1 paper

NM_006528.4

p.P161L

c.482C>T

1 paper

NM_006528.4

p.C158Y

c.473G>A

1 paper

NM_006528.4

p.S156_F157delFs

c.468_469delAT

1 paper

NM_006528.4

p.S156delFs

c.467delG

2 papers

NM_006528.4

p.T182T

c.546C>T

1 paper

NM_006528.4

p.C183Y

c.548G>A

2 papers

NM_006528.4

p.I154M

c.462T>G

1 paper

NM_006528.4

p.I154I

c.462T>A

1 paper

NM_006528.4

p.I154Splc

c.461-1G>A