Varaico: Literature-Extracted Genetic Variants

TFPI2

295 papers

RefSeq Summary

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin...

Pfam Domains

Kunitz_BPTIaa 35–87UCSCKunitz/Bovine pancreatic trypsin inhibitor domain

Kunitz_BPTIaa 95–150UCSCKunitz/Bovine pancreatic trypsin inhibitor domain

Kunitz_BPTIaa 157–209UCSCKunitz/Bovine pancreatic trypsin inhibitor domain

Gene Aliases

HGNC Name

tissue factor pathway inhibitor 2

HGNC Alias Symbols

PP5; TFPI-2; REF1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006528.4

p.P151L

c.452C>T

Surrounding Variants

1 paper

NM_006528.4

p.C149_A150del1

c.447_449delGCG

1 paper

NM_006528.4

p.I154insFs

c.460dupA

1 paper

NM_006528.4

p.M146R

c.437T>G

1 paper

NM_006528.4

p.D141fs

c.421_422fs

1 paper

NM_006528.4

p.I135S

c.404T>G

1 paper

NM_006528.4

p.R132Q

c.395G>A

1 paper

NM_006528.4

p.H131delFs

c.392delT

1 paper

NM_006528.4

p.G129W

c.385G>T

1 paper

NM_006528.4

p.F126L

c.378T>A

1 paper

NM_006528.4

p.F125I

c.373T>A

1 paper

NM_006528.4

p.D104Y

c.310G>T

1 paper

NM_006528.4

p.D103D

c.309C>T