Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 1776 variants

33 papers

NM_003235.5

p.R296*

c.886C>T

29 papers

NM_003235.5

p.F377F

c.1131T>C

27 papers

NM_003235.5

p.R1081R

c.3243A>G

24 papers

NM_003235.5

p.C1264R

c.3790T>C

22 papers

NM_003235.5

p.A2215D

c.6644C>A

21 papers

NM_003235.5

p.G381delFs

c.1143delC

19 papers

NM_003235.5

p.R1530*

c.4588C>T

19 papers

NM_003235.5

p.A2234D

c.6701C>A

19 papers

NM_003235.5

p.R2530Q

c.7589G>A

17 papers

NM_003235.5

p.C92Splc

c.274+2T>G

17 papers

NM_003235.5

p.S734A

c.2200T>G

17 papers

NM_003235.5

p.I2067Splc

c.6200-1G>C