Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003235.5

p.A359Splc

c.1076-2A>G

Surrounding Variants

3 papers

NM_003235.5

p.A359Splc

c.1076-1G>C

1 paper

NM_003235.5

p.A359D

c.1076C>A

3 papers

NM_003235.5

p.E360Q

c.1078G>C

1 paper

NM_003235.5

p.G361S

c.1081G>A

2 papers

NM_003235.5

p.G361D

c.1082G>A

1 paper

NM_003235.5

p.G361V

c.1082G>T

1 paper

NM_003235.5

p.Q362E

c.1084C>G

1 paper

NM_003235.5

p.C364G

c.1090T>G

1 paper

NM_003235.5

p.C364Y

c.1091G>A

1 paper

NM_003235.5

p.A365G

c.1094C>G

1 paper

NM_003235.5

p.A365A

c.1095C>A

1 paper

NM_003235.5

p.S366A

c.1096T>G