Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003235.5

p.Q370*

c.1108C>T

Surrounding Variants

1 paper

NM_003235.5

p.Q370_L372Fs

c.1108_1116delinsACAGFs

1 paper

NM_003235.5

p.Q369R

c.1106A>G

1 paper

NM_003235.5

p.R368R

c.1104G>A

1 paper

NM_003235.5

p.R368W

c.1102A>T

1 paper

NM_003235.5

p.L372delins

c.1116delinsACAG

1 paper

NM_003235.5

p.L372_S373delins

c.1116_1117delinsTG

1 paper

NM_003235.5

p.E367K

c.1099G>A

1 paper

NM_003235.5

p.S373P

c.1117T>C

1 paper

NM_003235.5

p.S373delFs

c.1118delC

1 paper

NM_003235.5

p.S366A

c.1096T>G

1 paper

NM_003235.5

p.A365A

c.1095C>A

1 paper

NM_003235.5

p.A365G

c.1094C>G