Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003235.5

p.G490D

c.1469G>A

Surrounding Variants

1 paper

NM_003235.5

p.T491I

c.1472C>T

1 paper

NM_003235.5

p.T491T

c.1473A>C

1 paper

NM_003235.5

p.R492_G493ins8

c.1474_1478ins24

2 papers

NM_003235.5

p.G493S

c.1477G>A

2 papers

NM_003235.5

p.G493R

c.1477G>C

1 paper

NM_003235.5

p.G487R

c.1459G>A

1 paper

NM_003235.5

p.G487R

c.1459G>C

1 paper

NM_003235.5

p.G487_A488insA

c.1459_1463ins3

1 paper

NM_003235.5

p.T494A

c.1480A>G

1 paper

NM_003235.5

p.N484S

c.1451A>G

1 paper

NM_003235.5

p.N484Y

c.1450A>T

1 paper

NM_003235.5

p.F483Y

c.1448T>A