Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003235.5

p.G533R

c.1597G>C

Surrounding Variants

1 paper

NM_003235.5

p.G533R

c.1597G>A

1 paper

NM_003235.5

p.T534N

c.1601C>A

1 paper

NM_003235.5

p.S531F

c.1592C>T

1 paper

NM_003235.5

p.S530T

c.1588T>A

1 paper

NM_003235.5

p.A537D

c.1610C>A

1 paper

NM_003235.5

p.A537G

c.1610C>G

1 paper

NM_003235.5

p.S528*

c.1583C>A

1 paper

NM_003235.5

p.S528*

c.1583C>G

1 paper

NM_003235.5

p.A538G

c.1613C>G

1 paper

NM_003235.5

p.G525G

c.1575A>G

1 paper

NM_003235.5

p.G525E

c.1574G>A

1 paper

NM_003235.5

p.D541E

c.1623T>A