Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003235.5

p.T543insFs

c.1628_1629insT

Surrounding Variants

1 paper

NM_003235.5

p.T543I

c.1628C>T

1 paper

NM_003235.5

p.T543S

c.1627A>T

1 paper

NM_003235.5

p.M544delFs

c.1630delA

1 paper

NM_003235.5

p.G542insFs

c.1625_1626ins4

1 paper

NM_003235.5

p.M544T

c.1631T>C

2 papers

NM_003235.5

p.G542S

c.1624G>A

1 paper

NM_003235.5

p.G542C

c.1624G>T

1 paper

NM_003235.5

p.D541E

c.1623T>A

1 paper

NM_003235.5

p.D541E

c.1623T>G

1 paper

NM_003235.5

p.N545S

c.1634A>G

1 paper

NM_003235.5

p.N545I

c.1634A>T

1 paper

NM_003235.5

p.K546T

c.1637A>C