Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003235.5

p.N557Y

c.1669A>T

Surrounding Variants

5 papers

NM_003235.5

p.I556V

c.1666A>G

1 paper

NM_003235.5

p.L558L

c.1672C>T

1 paper

NM_003235.5

p.E560K

c.1678G>A

2 papers

NM_003235.5

p.F552C

c.1655T>G

1 paper

NM_003235.5

p.Q562E

c.1684C>G

1 paper

NM_003235.5

p.F552L

c.1654T>C

1 paper

NM_003235.5

p.Q562P

c.1685A>C

2 papers

NM_003235.5

p.S551N

c.1652G>A

1 paper

NM_003235.5

p.N563_A564insT

c.1687_1691ins3

1 paper

NM_003235.5

p.G550A

c.1649G>C

1 paper

NM_003235.5

p.G550S

c.1648G>A

1 paper

NM_003235.5

p.A564A

c.1692C>T