Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_003235.5

p.G634R

c.1900G>A

Surrounding Variants

3 papers

NM_003235.5

p.G634R

c.1900G>C

1 paper

NM_003235.5

p.G634*

c.1900G>T

1 paper

NM_003235.5

p.G634E

c.1901G>A

2 papers

NM_003235.5

p.E635K

c.1903G>A

1 paper

NM_003235.5

p.E635G

c.1904A>G

2 papers

NM_003235.5

p.C631R

c.1891T>C

4 papers

NM_003235.5

p.W637*

c.1910G>A

5 papers

NM_003235.5

p.W637*

c.1911G>A

4 papers

NM_003235.5

p.Q630*

c.1888C>T

1 paper

NM_003235.5

p.C638Y

c.1913G>A

1 paper

NM_003235.5

p.D628V

c.1883A>T

1 paper

NM_003235.5

p.D628delFs

c.1883delA