Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

17 papers

NM_003235.5

p.S734A

c.2200T>G

Surrounding Variants

2 papers

NM_003235.5

p.S734T

c.2200T>A

1 paper

NM_003235.5

p.Q733H

c.2199G>T

3 papers

NM_003235.5

p.Q736*

c.2206C>T

1 paper

NM_003235.5

p.A737V

c.2210C>T

1 paper

NM_003235.5

p.P729S

c.2185C>T

5 papers

NM_003235.5

p.T728_P729insFs

c.2184_2185insA

4 papers

NM_003235.5

p.T728K

c.2183C>A

1 paper

NM_003235.5

p.R740S

c.2220G>C

1 paper

NM_003235.5

p.R740S

c.2220G>T

1 paper

NM_003235.5

p.T741_V742insA

c.2221_2225ins3

3 papers

NM_003235.5

p.T741M

c.2222C>T

1 paper

NM_003235.5

p.C726Y

c.2177G>A