Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003235.5

p.D757insFs

c.2269_2270insT

Surrounding Variants

2 papers

NM_003235.5

p.D757N

c.2269G>A

1 paper

NM_003235.5

p.D757delFs

c.2270delA

2 papers

NM_003235.5

p.S756_D757insFs

c.2268_2269insT

1 paper

NM_003235.5

p.Y759_I760insA

c.2275_2279ins3

4 papers

NM_003235.5

p.Y759C

c.2276A>G

1 paper

NM_003235.5

p.P761A

c.2281C>G

4 papers

NM_003235.5

p.P761S

c.2281C>T

1 paper

NM_003235.5

p.Q762delFs

c.2285_2286delAG

1 paper

NM_003235.5

p.D766_G767delFs

c.2296_2299del4

1 paper

NM_003235.5

p.D766_G767Fs

c.2298_2301delinsAAAGTAFs

1 paper

NM_003235.5

p.G767R

c.2299G>A

2 papers

NM_003235.5

p.G767insFs

c.2299_2300insC