Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

27 papers

NM_003235.5

p.R1081R

c.3243A>G

Surrounding Variants

1 paper

NM_003235.5

p.R1081R

c.3243A>T

1 paper

NM_003235.5

p.R1081Q

c.3242G>A

1 paper

NM_003235.5

p.R1081*

c.3241C>T

1 paper

NM_003235.5

p.R1081delFs

c.3241_3242delCG

1 paper

NM_003235.5

p.E1078A

c.3233A>C

1 paper

NM_003235.5

p.C1077*

c.3231C>A

1 paper

NM_003235.5

p.L1085L

c.3255G>A

3 papers

NM_003235.5

p.L1086F

c.3256C>T

10 papers

NM_003235.5

p.C1077R

c.3229T>C

1 paper

NM_003235.5

p.S1088R

c.3264T>A

1 paper

NM_003235.5

p.W1089*

c.3266G>A

1 paper

NM_003235.5

p.W1089*

c.3267G>A