Varaico: Literature-Extracted Genetic Variants

TG

2,250 papers

RefSeq Summary

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the in...

Pfam Domains

Thyroglobulin_1aa 34–92UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 96–160UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 301–358UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 597–658UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 662–726UCSCThyroglobulin type-1 repeat

Thyroglobulin_1aa 730–799UCSCThyroglobulin type-1 repeat

Gene Aliases

HGNC Name

thyroglobulin

HGNC Alias Symbols

TGN; AITD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003235.5

p.C1543S

c.4627T>A

Surrounding Variants

1 paper

NM_003235.5

p.F1542F

c.4626C>T

1 paper

NM_003235.5

p.C1543S

c.4628G>C

1 paper

NM_003235.5

p.C1543*

c.4629T>A

1 paper

NM_003235.5

p.F1542V

c.4624T>G

1 paper

NM_003235.5

p.F1542fs

c.4624_4625fs

1 paper

NM_003235.5

p.A1541_F1542insFs

c.4623_4624insG

1 paper

NM_003235.5

p.K1540N

c.4620G>T

1 paper

NM_003235.5

p.E1547D

c.4641G>T

1 paper

NM_003235.5

p.G1548W

c.4642G>T

1 paper

NM_003235.5

p.G1537D

c.4610G>A

1 paper

NM_003235.5

p.R1536S

c.4608G>T

1 paper

NM_003235.5

p.R1536M

c.4607G>T