Varaico: Literature-Extracted Genetic Variants

Gene:TGFB1
Variant:p.P10insFs

TGFB1

1,279 papers

RefSeq Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activat...

Pfam Domains

TGFb_propeptideaa 30–261UCSCTGF-beta propeptide
TGF_betaaa 292–389UCSCTransforming growth factor beta like domain

Gene Aliases

HGNC Name

transforming growth factor beta 1

HGNC Previous Symbol

DPD1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000660.7
p.P10insFs
c.29_30insT
Surrounding Variants
84 papers
NM_000660.7
p.P10L
c.29C>T
1 paper
NM_000660.7
p.P10R
c.29C>G
1 paper
NM_000660.7
p.P10fs
c.28_29fs
1 paper
NM_000660.7
p.P10P
c.30G>A
1 paper
NM_000660.7
p.P10A
c.28C>G
1 paper
NM_000660.7
p.P10insFs
c.28_29insTG
1 paper
NM_000660.7
p.L9L
c.27G>A
1 paper
NM_000660.7
p.L11Q
c.32T>A
4 papers
NM_000660.7
p.P10del1
c.28_29delCGG
1 paper
NM_000660.7
p.L11L
c.33G>T
6 papers
NM_000660.7
p.L9V
c.25C>G
1 paper
NM_000660.7
p.L12ins3
c.35_36ins9
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."