Varaico: Literature-Extracted Genetic Variants

TGFBR2

1,068 papers

RefSeq Summary

The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand comp...

Pfam Domains

ecTbetaR2aa 14–124UCSCTransforming growth factor beta receptor 2 ectodomain

PK_Tyr_Ser-Thraa 209–503UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

transforming growth factor beta receptor 2

HGNC Previous Symbol

MFS2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

36 papers

NM_003242.6

p.G357W

c.1069G>T

Surrounding Variants

5 papers

NM_003242.6

p.G357R

c.1069G>A

5 papers

NM_003242.6

p.G357R

c.1069G>C

1 paper

NM_003242.6

p.R356Q

c.1067G>A

16 papers

NM_001024847.3

p.R381P

c.1142G>C

NM_003242.6

p.R356P

c.1067G>C

1 paper

NM_003242.6

p.I358L

c.1072A>C

4 papers

NM_003242.6

p.R356G

c.1066C>G

4 papers

NM_003242.6

p.R356W

c.1066C>T

1 paper

NM_003242.6

p.A355T

c.1063G>A

16 papers

NM_001024847.3

p.A380P

c.1138G>C

NM_003242.6

p.A355P

c.1063G>C

1 paper

NM_003242.6

p.A359_H360insAAC

c.1075_1079ins9

3 papers

NM_001024847.3

p.L379L

c.1137C>T

NM_003242.6

p.L354L

c.1062C>T

1 paper

NM_003242.6

p.A359V

c.1076C>T