Varaico: Literature-Extracted Genetic Variants

THOC2

109 papers

RefSeq Summary

The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded ...

Pfam Domains

THOC2_Naa 8–426UCSCTHO complex subunit 2 N-terminus

THOC2_Naa 415–566UCSCTHO complex subunit 2 N-terminus

Thoc2aa 568–643UCSCTranscription- and export-related complex subunit

Tho2aa 873–1173UCSCTranscription factor/nuclear export subunit protein 2

Gene Aliases

HGNC Name

THO complex subunit 2

HGNC Previous Symbols

MRX12; MRX35

Papers

RefSeq ID

Protein change

DNA change

1–12 of 129 variants

7 papers

NM_001081550.2

p.Y517C

c.1550A>G

5 papers

NM_001081550.2

p.R77C

c.229C>T

5 papers

NM_001081550.2

p.L438P

c.1313T>C

4 papers

NM_001081550.2

p.L313F

c.937C>T

4 papers

NM_001081550.2

p.I800T

c.2399T>C

4 papers

NM_001081550.2

p.S1012P

c.3034T>C

3 papers

NM_001081550.2

p.A421T

c.1261G>A

3 papers

NM_001081550.2

p.G713D

c.2138G>A

3 papers

NM_001081550.2

p.S1108L

c.3323C>T

3 papers

NM_001081550.2

p.R1121G

c.3361A>G

3 papers

NM_001081550.2

p.G1168Splc

c.3503+4A>C

3 papers

NM_001081550.2

p.H1187Y

c.3559C>T