Varaico: Literature-Extracted Genetic Variants

THOC2

109 papers

RefSeq Summary

The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded ...

Pfam Domains

THOC2_Naa 8–426UCSCTHO complex subunit 2 N-terminus

THOC2_Naa 415–566UCSCTHO complex subunit 2 N-terminus

Thoc2aa 568–643UCSCTranscription- and export-related complex subunit

Tho2aa 873–1173UCSCTranscription factor/nuclear export subunit protein 2

Gene Aliases

HGNC Name

THO complex subunit 2

HGNC Previous Symbols

MRX12; MRX35

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001081550.2

p.D1413Y

c.4237G>T

Surrounding Variants

1 paper

NM_001081550.2

p.S1388P

c.4162T>C

1 paper

NM_001081550.2

p.T1385fs

c.4153_4154fs

1 paper

NM_001081550.2

p.G1381fs

c.4141_4142fs

1 paper

NM_001081550.2

p.G1381delFs

c.4142delC

1 paper

NM_001081550.2

p.K1374R

c.4121A>G

1 paper

NM_001081550.2

p.K1371R

c.4112A>G

1 paper

NM_001081550.2

p.I1369M

c.4107A>G

1 paper

NM_001081550.2

p.R1307W

c.3919C>T

1 paper

NM_001081550.2

p.K1279R

c.3836A>G

1 paper

NM_001081550.2

p.E1430D

c.4290A>T

1 paper

NM_001081550.2

p.E1430D

c.4290A>C

1 paper

NM_001081550.2

p.E1433D

c.4299A>T